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Joan W Miller Selected Research

Verteporfin (Visudyne)

1/2017Verteporfin inhibits growth of human glioma in vitro without light activation.
1/2017Verteporfin-induced formation of protein cross-linked oligomers and high molecular weight complexes is mediated by light and leads to cell toxicity.
7/2014The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation.
11/2010Treatment of age-related macular degeneration: beyond VEGF.
1/2008Higher irradiance and photodynamic therapy for age-related macular degeneration (an AOS thesis).
6/2006Investigating the effect of ciliary body photodynamic therapy in a glaucoma mouse model.
9/2005Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration: four-year results of an open-label extension of 2 randomized clinical trials: TAP Report No. 7.
4/2005Safety and efficacy of intravitreal injection of ranibizumab in combination with verteporfin PDT on experimental choroidal neovascularization in the monkey.
7/2004Selective photodynamic therapy by targeted verteporfin delivery to experimental choroidal neovascularization mediated by a homing peptide to vascular endothelial growth factor receptor-2.
4/2004Acute severe visual acuity decrease after photodynamic therapy with verteporfin: case reports from randomized clinical trials-TAP and VIP report no. 3.
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Joan W Miller Research Topics

Disease

45Macular Degeneration (Age-Related Maculopathy)
04/2022 - 03/2002
30Choroidal Neovascularization
11/2019 - 03/2002
17Retinal Detachment (Retinal Detachments)
01/2021 - 03/2003
17Inflammation (Inflammations)
01/2020 - 03/2002
9Diabetic Retinopathy (Retinopathy, Diabetic)
06/2022 - 02/2007
9Neoplasms (Cancer)
01/2017 - 07/2007
7Glaucoma
07/2022 - 09/2002
7Retinoblastoma (Glioblastoma, Retinal)
12/2014 - 01/2005
5Eye Diseases (Eye Disease)
03/2016 - 02/2005
5Uveitis
06/2012 - 07/2007
4Atrophy
10/2021 - 05/2012
4Geographic Atrophy
06/2021 - 09/2010
4Pathologic Neovascularization
11/2019 - 08/2003
4Necrosis
11/2013 - 07/2004
3Retinal Vein Occlusion
04/2022 - 02/2005
3Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 04/2004
3Myopia
08/2021 - 04/2003
3Cataract (Cataracts)
01/2019 - 01/2010
3Uveal melanoma
01/2017 - 04/2014
3Infections
04/2013 - 09/2005
3Ganglion Cysts (Ganglion)
08/2006 - 02/2005
2Blindness (Hysterical Blindness)
01/2022 - 01/2014
2Vision Disorders (Hemeralopia)
03/2021 - 07/2015
2Retinal Diseases
01/2021 - 06/2007
2Corneal Neovascularization
11/2019 - 07/2012
2Wounds and Injuries (Trauma)
01/2019 - 09/2014
2Hemorrhage
01/2019 - 03/2002
2Neuroinflammatory Diseases
01/2019 - 01/2018
2Retinal Neovascularization
01/2014 - 08/2003
2Endophthalmitis (Ophthalmia)
04/2013 - 09/2005
2Retinitis Pigmentosa (Pigmentary Retinopathy)
09/2012 - 06/2011
2Multiple Sclerosis
10/2011 - 02/2007
2Back Pain (Backache)
02/2004 - 10/2002
1Herpetic Keratitis
11/2022
1Dyslipidemias (Dyslipidemia)
01/2022
1Strabismus (Squint)
01/2022
1Mitochondrial Diseases (Mitochondrial Disease)
03/2021
1Fibrosis (Cirrhosis)
12/2019

Drug/Important Bio-Agent (IBA)

20Retinaldehyde (Retinal)IBA
10/2021 - 08/2003
19Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 03/2002
14Verteporfin (Visudyne)FDA Link
01/2017 - 07/2002
111-phenyl-3,3-dimethyltriazene (PDT)IBA
11/2010 - 07/2002
7Phosphotransferases (Kinase)IBA
11/2019 - 08/2010
6Fluorescein (Funduscein)FDA LinkGeneric
01/2021 - 04/2003
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020 - 08/2006
6Pharmaceutical PreparationsIBA
12/2014 - 10/2007
5Hyaluronic Acid (Hyaluronan)IBA
05/2014 - 03/2003
5AICA ribonucleotide (ZMP)IBA
04/2014 - 08/2010
5Complement Factor H (Factor H)IBA
10/2011 - 01/2007
5CaspasesIBA
06/2011 - 03/2003
4Complement System Proteins (Complement)IBA
04/2022 - 12/2016
4LipidsIBA
01/2022 - 12/2016
4Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2022 - 06/2006
4Proteins (Proteins, Gene)FDA Link
11/2019 - 07/2008
4EndotoxinsIBA
08/2011 - 07/2007
3Biomarkers (Surrogate Marker)IBA
06/2022 - 08/2008
3InflammasomesIBA
01/2019 - 12/2016
3CytokinesIBA
11/2015 - 11/2005
3Adenosine Monophosphate (AMP)IBA
04/2014 - 08/2010
3Ranibizumab (Lucentis)FDA Link
07/2013 - 04/2005
3Receptor-Interacting Protein Serine-Threonine KinasesIBA
09/2012 - 12/2010
3Cell Adhesion MoleculesIBA
08/2008 - 06/2003
3Immunoglobulin FragmentsIBA
06/2005 - 03/2002
2Fatty Acids (Saturated Fatty Acids)IBA
03/2021 - 01/2007
2Indicators and Reagents (Reagents)IBA
11/2018 - 07/2011
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2017 - 11/2010
2Protons (Proton)IBA
09/2014 - 11/2006
2Photosensitizing Agents (Photosensitizers)IBA
07/2014 - 01/2004
2CyclinsIBA
04/2014 - 01/2013
2Protein Kinases (Protein Kinase)IBA
11/2013 - 12/2010
2Bevacizumab (Avastin)FDA Link
07/2013 - 11/2011
2Biological ProductsIBA
10/2011 - 03/2009
2Peptide Hydrolases (Proteases)FDA Link
10/2011 - 07/2008
2Serine (L-Serine)FDA Link
10/2011 - 07/2008
2Caspase 9IBA
06/2008 - 12/2004
2Cytochromes c (Cytochrome c)IBA
06/2008 - 12/2004
2Caspase 8 (Caspase-8)IBA
01/2005 - 12/2004
2Monoclonal AntibodiesIBA
01/2005 - 03/2002
1Complement Inactivating AgentsIBA
06/2021
1Amino AcidsFDA Link
03/2021
1Glycerophospholipids (Phosphoglycerides)IBA
03/2021
1Complement C3 (C3 Complement)IBA
01/2020
1matrigelIBA
11/2019
1AlkaliesIBA
11/2019
1necrostatin-1IBA
11/2019
1Capsules (Microcapsules)IBA
01/2019

Therapy/Procedure

20Photochemotherapy (Photodynamic Therapy)
01/2021 - 07/2002
19Therapeutics
06/2021 - 10/2002
16Lasers (Laser)
11/2019 - 05/2002
6Intravitreal Injections
04/2022 - 03/2002
3Trabeculectomy (Trabeculoplasty)
07/2022 - 11/2021
3Vitrectomy
01/2019 - 09/2002
2Operative Surgical Procedures
01/2022 - 09/2016
2Intraocular Lenses (Intraocular Lens)
01/2019 - 09/2005
2Intraperitoneal Injections
11/2016 - 01/2013
2Injections
04/2013 - 03/2002
1Corneal Transplantation (Keratoplasty)
11/2022
1Phacoemulsification
07/2022
1Suture Techniques
01/2022
1Sutures (Suture)
01/2022